Pilot and Feasibility Grants
The goals of the Pilot and Feasibility Grants are to:
- Extend the activities of the Clinical Research Network to new investigators;
- Enhance efficiency in research by supporting ancillary studies (studies funded by the Clinical Research Network and by other JDRF and non-JDRF schemes are eligible);
- Assist with trial initiation by supporting pilot data collection;
- Accelerate research towards clinical translation;
- Support current Clinical Research Network-funded investigators.
Applicants may request approximately $80,000 of total costs (including 10% indirect costs) of P&F Grants funding. The project should be completed within one year, starting from the time of funds disbursement but no later than 31 December, 2014.
The P&F Grant scheme will aim to fund at least four P&F grants.
Applications may be submitted by:
- Investigators and institutions based in Australia;
- Public or private, such as research institutes, universities, hospitals, laboratories, eligible domestic non-profit organisations based in Australia;
- Agencies of governments;
- Australian biotech or for-profit organisations.
Academic-type applications must be made by a Principal Investigator/s holding an M.D., Ph.D., or equivalent academic degree and hold a position or equivalent at an Australian-based college, university, medical school, or comparable institution.
Collaborations between institutions, investigators and industry, especially those intended to add to the Clinical Research Network infrastructure and/or research resources are encouraged.
Funded Pilot & Feasibility Grants
|Lead Institution||Project Title||Impact on people with type 1 diabetes|
|NHMRC Clinical Trials Centre||A clinical study for validating beta cell death in type 1 diabetes||This project will lead to the development of new tools and procedures that could be used to detect the loss of insulin-producing beta cells from an early stage. In doing so, it may allow the use of interventional therapies to preserve remaining beta cell function in people with type 1 diabetes.|
|University of Technology Sydney||Telehealth to support insulin pump users in regional and rural Australia||By creating a small-scale service model to provide specialist care to insulin pump users in regional and rural NSW, this project has the potential to expand its impact to reduce the current gap between the availability of specialist services between urban and rural regions all across Australia.|
|Murdoch Children's Research Institute||Exploring the acute impact of hypo & hyperglycaemia on brain function in T1D||This project aims to understand the impact of fluctuating blood glucose levels on brain function. In doing so, the results obtained from this study will guide clinical management of type 1 diabetes in improving overall quality of life and developmental outcomes in young patients.|
|Garvan Institute of Medical Research||Islet epigenetic programming and reprogramming during transplantation||This project will use advanced approaches to generate a map of the genetic changes in islets during the stress of transplantation. This will generate new data which may result in new therapies to improve the function of transplanted islets and provide potential markers to track this function.|
|Centre for Eye Research Australia Limited||Retinal vascular function during hyperglycaemia and the role of vitamin C||This study will provide insight into whether vitamin C can affect blood flow in the eye during episodes of high blood sugar. In doing so, it has the potential to develop into a larger clinical trial to use vitamin C to reduce the risk of diabetic complications.|
|Garvan Institute of Medical Research||Machine-Intelligent Artificial Pancreas System||Using an artificial intelligence-inspired system, this project aims to enhance the usage of the artificial pancreas, bringing us one step closer to a true ‘closed-loop’ system|
|Baker IDI Heart and Diabetes Institute||Elucidating mitochondrial defects in human diabetic nephropathy||By investigating the role of the power-houses of cells in the kidneys of people with type 1 diabetes, this study may lead to the development of new targets to treat kidney disease.|
|The University of Sydney||Type 1 Diabetes and Exercise RCT of an On-Line Educational Tool||This study will determine if an online educational tool in type 1 diabetes and exercise is able to improve outcomes for people with type 1 diabetes, thus creating an evidence base related to blood glucose stability around exercise and confidence to exercise.|
|Jointly: The Australasian Paediatric Endocrine Group, The University of Queensland Diamantina Institute, and The University of Western Australia||Collaborative Biospecimen Data Linkage Project||This project will begin to collect and connect bio samples to the ADDN database. This connection will help with understanding disease mechanisms and connecting immunological, genetic and other biomarkers with clinical symptoms.|