The T1DCRN supports new and promising ideas in type 1 diabetes clinical research to drive the growth of revolutionary concepts.

Each Pilot and Feasibility (P & F) grant was funded for the project's potential to make an impact on the lives of people living with type 1 diabetes.

The P & F grants completed in 2015. Stay tuned for research outcomes from these projects.

Preserving beta cell function

NHMRC Clinical Trials Centre, Sydney

This project will lead to the development of new tools and procedures that could be used to detect the loss of insulin-producing beta cells from an early stage. In doing so, it may allow the use of interventional therapies to preserve remaining beta cell function in people with type 1 diabetes.

Providing specialist support for rural insulin pump users

University of Technology, Sydney

This project follows a small-scale service model to provide specialist care to insulin pump users in regional and rural NSW.

Understanding the impact of hypo and hyperglycaemia on brain function

Murdoch Children's Research Institute, Melbourne

This project aims to understand the impact of fluctuating blood glucose levels on brain function. In doing so, the results obtained from this study will guide clinical management of type 1 diabetes in improving overall quality of life and developmental outcomes in young patients.

Improving the function of transplanted islets

Garvan Institute of Medical Research, Sydney

This project will use advanced approaches to generate a map of the genetic changes in islets during the stress of transplantation. This will generate new data which may result in new therapies to improve the function of transplanted islets and provide potential markers to track this function.

Looking at the role of mitochondria for potential kidney disease treatments

Baker IDI Heart and Diabetes Institute, Melbourne

By investigating the role of the power-houses of cells in the kidneys of people with type 1 diabetes, this study may lead to the development of new targets to treat kidney disease.

Using an online educational tool to test the link between blood glucose stability and exercise

The University of Sydney

This study will determine if an online educational tool in type 1 diabetes and exercise is able to improve outcomes for people with type 1 diabetes, thus creating an evidence base related to blood glucose stability around exercise and confidence to exercise.

Discovering the impact of vitamin C on blood flow in the eye during hyperglycaemia

Centre for Eye Research Australia, Melbourne

This study will provide insight into whether vitamin C can affect blood flow in the eye during episodes of high blood sugar. In doing so, it has the potential to develop into a larger clinical trial to use vitamin C to reduce the risk of diabetic complications.

Using AI to enhance the usage of the artificial pancreas

Garvan Institute of Medical Research

Using an artificial intelligence-inspired system, this project aims to enhance the usage of the artificial pancreas, bringing us one step closer to a true ‘closed-loop’ system.

Understanding type 1 diabetes through a biospecimens database

The Australasian Paediatric Endocrine Group, The University of Queensland Diamantina Institute, and The University of Western Australia

This project will begin to collect and connect bio samples to the ADDN database. This connection will help with understanding disease mechanisms and connecting immunological, genetic and other biomarkers with clinical symptoms.